Lihong Wang
Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering
Research interests: photoacoustic tomography (microscopy and computed tomography), thermoacoustic tomography, light-speed compressed ultrafast photography, time-reversal optics/wavefront shaping, quantum imaging and physics
Overview
Professor Wang's research focuses on biomedical imaging. In particular, his lab has developed photoacoustic imaging that allows peering noninvasively into biological tissues. Compared to conventional optical microscopy, his techniques have increased the penetration by nearly two orders of magnitude, breaking through the optical diffusion limit. The Wang lab has invented or discovered functional photoacoustic tomography, 3D photoacoustic microscopy, optical-resolution photoacoustic microscopy, photoacoustic Doppler effect, photoacoustic reporter gene imaging, microwave-induced thermoacoustic tomography, universal photoacoustic reconstruction algorithm, time-reversed ultrasonically encoded optical focusing, and compressed ultrafast photography (world's fastest camera capable of 10 trillion frames per second). Combining rich optical contrast and scalable ultrasonic resolution, photoacoustic imaging is the only modality capable of providing multiscale high-resolution structural, functional, metabolic, and molecular imaging of organelles, cells, tissues, and organs as well as small-animal organisms in vivo. Broad applications include early-cancer detection, surgical guidance, and brain imaging. For example, it can help surgeons effectively remove breast cancer lumps, reducing the need for follow-up surgeries. Professor Wang's Monte Carlo model of photon transport in scattering media is used worldwide as a standard tool.
Related News
Read more newsPublications
- Han, Hong;Ma, Xiaotian et al. (2024) Imaging-guided bioresorbable acoustic hydrogel microrobotsScience Robotics
- Park, Jeongwoo;Choi, Seongwook et al. (2024) Clinical translation of photoacoustic imagingNature Reviews Bioengineering
- Mishra, Yogeshwar Nath;Wang, Peng et al. (2024) Single-pulse ultrafast real-time simultaneous planar imaging of femtosecond laser-nanoparticle dynamics in flamesLight: Science and Applications
- Loh, Kang Yong;Li, Lei S. et al. (2024) Sharp-peaked lanthanide nanocrystals for near-infrared photoacoustic multiplexed differential imagingCommunications Materials
- Kahraman, S. Süleyman;Titimbo, Kelvin et al. (2024) Quantum mechanical modeling of the multi-stage Stern–Gerlach experiment conducted by Frisch and SegrèNew Journal of Physics
- Hu, Peng;Zhao, Peinan et al. (2024) Quantification of Cervical Elasticity During Pregnancy Based on Transvaginal Ultrasound Imaging and Stress MeasurementIEEE Transactions on Biomedical Engineering
- Dey, Sreemanti;Saha, Snigdha et al. (2024) Score-based Diffusion Models for Photoacoustic Tomography Image Reconstruction
- Zhang, Yide;He, Zhe et al. (2024) Quantum imaging of biological organisms through spatial and polarization entanglementScience Advances
- Shen, Yuecheng;Ma, Jun et al. (2024) Acoustic-feedback wavefront-adapted photoacoustic microscopyOptica
- Hu, Peng;Tong, Xin et al. (2024) Data-driven system matrix manipulation enabling fast functional imaging and intra-image nonrigid motion correction in tomography