Dual appointments in Biological Engineering and Medical Engineering
Research Group Manager: Natasha Shelby
Ismagilov Group is passionate about bringing creativity, science and technology to solve problems in global health. Members of our Group have backgrounds in chemistry, biology, medicine, biophysics and multiple areas of engineering—creating a rich, interdisciplinary and collaborative environment. We collaborate with other researchers, clinical teams, industry, and other stakeholders to translate our research into impact.
We are interested in interactions of microbes with the human host in a wide range of contexts, from infection to beneficial colonization to everything in between. For example, in the context of infections, we develop rapid diagnostics of infectious diseases (including several COVID-19 related projects). In another example, in the context of colonization, we work to understand the interplay of food, gut microbes, and biophysics in human health. One of our unique strengths is that we develop novel technologies to enable high-resolution quantitative measurements and computational analyses that haven't previously been possible, but are necessary to understand complex systems like the human-microbe interface.
We engage in both fundamental research (to understand these complex systems) and translational research to make real-world impact. Our lab culture is one of scientific rigor, creativity, collaboration, and strong mutual support.
Publications
- Wu-Woods, Natalie J.;Barlow, Jacob T. et al. (2023) Microbial-enrichment method enables high-throughput metagenomic characterization from host-rich samplesNature Methods
- Ji, Jenny;Viloria Winnett, Alexander et al. (2023) Index cases first identified by nasal-swab rapid COVID-19 tests had more transmission to household contacts than cases identified by other test typesPLOS ONE
- Poceviciute, Roberta;Bogatyrev, Said R. et al. (2023) Quantitative whole-tissue 3D imaging reveals bacteria in close association with mouse jejunum mucosanpj Biofilms and Microbiomes
- Winnett, Alexander Viloria;Akana, Reid et al. (2023) Daily SARS-CoV-2 Nasal Antigen Tests Miss Infected and Presumably Infectious People Due to Viral Load Differences among Specimen TypesMicrobiology Spectrum
- Ji, Jenny;Winnett, Alexander Viloria et al. (2023) Index Cases First Identified by Nasal-Swab Rapid COVID-19 Tests Had More Transmission to Household Contacts Than Cases Identified by Other Test Types
- Winnett, Alexander Viloria;Akana, Reid et al. (2023) Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periodsPNAS Nexus
- Carter, Alyssa M.;Winnett, Alexander Viloria et al. (2023) Laboratory Evaluation Links Some False-Positive COVID-19 Antigen Test Results Observed in a Field Study to a Specific Lot of Test StripsOpen Forum Infectious Diseases
- Earley, Zachary M.;Lisicka, Wioletta et al. (2023) GATA4 controls regionalization of tissue immunity and commensal-driven immunopathologyImmunity
- Winnett, Alexander Viloria;Porter, Michael K. et al. (2022) Morning SARS-CoV-2 Testing Yields Better Detection of Infection Due to Higher Viral Loads in Saliva and Nasal Swabs upon WakingMicrobiology Spectrum
- Winnett, Alexander Viloria;Akana, Reid et al. (2022) Why Daily SARS-CoV-2 Nasal Rapid Antigen Testing Poorly Detects Infected and Infectious Individuals
2022-23
Instructor: Ismagilov
Instructors: Flagan, Ismagilov
2021-22
Instructor: Ismagilov
2019-20
Instructor: Ismagilov
Instructors: Gavalas, Ismagilov