Research Summary
Magnetic resonance imaging, gene expression, neuroanatomy
Profile
Biology of Neurodegenerative Disorders
We are investigating the biology of neurodegenerative disorders in normal elderly and people with Alzheimer's disease and frontotemporal dementia in collaboration with Professors Barbara Wold and Long Cai and their laboratories untilizing RNA-Seq, Seq-FISH and immunocytochemistry, and Dr.Ryan Cabeen using high angular resolution diffusion magnetic resonance imaging. Our data reveal reduction in the capacity to maintain healthy axons in these dementias that could be part of the pathogenesis of these disorders.
Publications
Books
- The Human Illnesses by Peter C. Williamson and John Allman, Oxford University Press, New York, 2011.
- Evolving Brains by John Allman, Scientific American Library - W. H. Freeman, New York, 2000. Download